Treatment of Immunocompromised, Critically Ill Patients with Influenza A H1N1 Infection with a Combination of Oseltamivir, Amantadine, and Zanamivir
Joint Authors
Kromdijk, Wiete
van den Broek, Marcel P. H.
Haas, Pieter-Jan A.
Minnema, Monique C.
Boucher, Charles A.
de Lange, Dylan W.
Wensing, Annemarie M. J.
Meijer, Wouter J.
Source
Case Reports in Infectious Diseases
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-09
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Immunocompromised patients are at increased risk of complications of influenza virus infection.
We report on two critically ill patients on immunosuppressive medication with influenza pneumonia.
In both patients, oseltamivir monotherapy did not result in clearance of the virus after 18 and five days, respectively.
After adding zanamivir and amantadine to the treatment, PCRs on pharyngeal and/or plasma specimens turned negative in both patients after four and three days, respectively.
We suggest, that in critically ill patients with influenza A H1N1 infection, treatment efficacy should be monitored closely and treatment with a combination of antiviral drugs should be considered.
American Psychological Association (APA)
Meijer, Wouter J.& Kromdijk, Wiete& van den Broek, Marcel P. H.& Haas, Pieter-Jan A.& Minnema, Monique C.& Boucher, Charles A.…[et al.]. 2015. Treatment of Immunocompromised, Critically Ill Patients with Influenza A H1N1 Infection with a Combination of Oseltamivir, Amantadine, and Zanamivir. Case Reports in Infectious Diseases،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1058721
Modern Language Association (MLA)
Meijer, Wouter J.…[et al.]. Treatment of Immunocompromised, Critically Ill Patients with Influenza A H1N1 Infection with a Combination of Oseltamivir, Amantadine, and Zanamivir. Case Reports in Infectious Diseases No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1058721
American Medical Association (AMA)
Meijer, Wouter J.& Kromdijk, Wiete& van den Broek, Marcel P. H.& Haas, Pieter-Jan A.& Minnema, Monique C.& Boucher, Charles A.…[et al.]. Treatment of Immunocompromised, Critically Ill Patients with Influenza A H1N1 Infection with a Combination of Oseltamivir, Amantadine, and Zanamivir. Case Reports in Infectious Diseases. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1058721
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1058721