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Bone Marrow Granuloma in Typhoid Fever: A Morphological Approach and Literature Review
Joint Authors
Padhi, Somanath
Muniraj, Kavitha
Phansalkar, Manjiri
Sivakumar, Periyasami
Varghese, Renu G’Boy
Kanungo, Reba
Source
Case Reports in Infectious Diseases
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-19
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Typhoid fever is one of the few bacterial infections in humans where bone marrow evaluation is routinely recommended.
However, the morphological aspect of typhoid fever in bone marrow has been rarely described in the literature.
We describe a 25-year-old male patient who presented with prolonged fever suspected to be of tubercular etiology.
Bone marrow examination showed well-formed histiocytic and epithelioid granulomas and erythrophagocytosis; and the bone marrow aspirate culture grew Salmonella typhi A.
In view of potential clinical implications, typhoid fever should be considered as a differential diagnosis to tuberculosis in the evaluation of prolonged fever; especially in high prevalent areas.
We suggest that erythrophagocytosis may serve as a morphological marker in typhoid granulomas in the bone marrow; and bone marrow culture should be submitted in every suspected case for appropriate patient management.
American Psychological Association (APA)
Muniraj, Kavitha& Padhi, Somanath& Phansalkar, Manjiri& Sivakumar, Periyasami& Varghese, Renu G’Boy& Kanungo, Reba. 2015. Bone Marrow Granuloma in Typhoid Fever: A Morphological Approach and Literature Review. Case Reports in Infectious Diseases،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1058737
Modern Language Association (MLA)
Muniraj, Kavitha…[et al.]. Bone Marrow Granuloma in Typhoid Fever: A Morphological Approach and Literature Review. Case Reports in Infectious Diseases No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1058737
American Medical Association (AMA)
Muniraj, Kavitha& Padhi, Somanath& Phansalkar, Manjiri& Sivakumar, Periyasami& Varghese, Renu G’Boy& Kanungo, Reba. Bone Marrow Granuloma in Typhoid Fever: A Morphological Approach and Literature Review. Case Reports in Infectious Diseases. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1058737
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1058737