Cutaneous Ulcer as Leading Symptom of Systemic Cytomegalovirus Infection
Joint Authors
Guo, Richard F.
Gebreab, Frew H.
Tang, Emily Hsiang-Ho
Piao, Zhe
Lee, Steve S.
Perez, Mario L.
Source
Case Reports in Infectious Diseases
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-16
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Cytomegalovirus (CMV) infection rarely manifests with skin ulcerations.
We describe a case report of a 64-year-old woman with chronic immunosuppression for treatment of mixed connective tissue disease, presenting with new onset leg ulcerations after a recent change in immunosuppressive regimen.
She subsequently developed fulminant hepatitis, encephalopathy, and pancytopenia and was found to have severe systemic CMV viremia.
Skin ulcer biopsy was positive by immunohistochemical staining for CMV infected endothelial cells.
Both systemic disease and skin ulcer rapidly improved after stopping immunosuppression and administering intravenous ganciclovir.
New onset skin ulcers in an immunosuppressed individual, especially with recent changes in immunosuppressive regimen, should raise the suspicion of reactivation of CMV.
American Psychological Association (APA)
Guo, Richard F.& Gebreab, Frew H.& Tang, Emily Hsiang-Ho& Piao, Zhe& Lee, Steve S.& Perez, Mario L.. 2015. Cutaneous Ulcer as Leading Symptom of Systemic Cytomegalovirus Infection. Case Reports in Infectious Diseases،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1058749
Modern Language Association (MLA)
Guo, Richard F.…[et al.]. Cutaneous Ulcer as Leading Symptom of Systemic Cytomegalovirus Infection. Case Reports in Infectious Diseases No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1058749
American Medical Association (AMA)
Guo, Richard F.& Gebreab, Frew H.& Tang, Emily Hsiang-Ho& Piao, Zhe& Lee, Steve S.& Perez, Mario L.. Cutaneous Ulcer as Leading Symptom of Systemic Cytomegalovirus Infection. Case Reports in Infectious Diseases. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1058749
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1058749