Fatal Case of Probable Invasive Aspergillosis after Five Years of Heart Transplant: A Case Report and Review of the Literature
Joint Authors
Anantha Narayanan, Mahesh
Mahfood Haddad, Toufik
Shaw, Krista E.
Vivekanandan, Renuga
Source
Case Reports in Infectious Diseases
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-24
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Invasive fungal infections are very common in solid organ transplants and occur most frequently in the first three months after transplant.
A 49-year-old female with a history of two remote heart transplants with the most recent one occurring 5 years ago was admitted for increasing shortness of breath, cough, and fever.
Computerized tomography (CT) scan of the chest showed left lower lung ground-glass and tree-in-bud opacities.
She was started on broad spectrum antibiotics along with ganciclovir and micafungin.
Ganciclovir was added due to the patient’s past history of CMV infection and empiric fungal coverage with micafungin.
Bronchoalveolar lavage (BAL) was performed as her respiratory status worsened and voriconazole was added for possible aspergillosis in combination therapy with micafungin.
BAL galactomannan returned positive which was suggestive of aspergillosis.
Patient worsened clinically and subsequently succumbed to cardiorespiratory arrest despite our best efforts.
It is important to have a high degree of clinical suspicion for invasive aspergillosis in transplant patients even many years after transplant and initiate aggressive therapy due to poor outcomes.
American Psychological Association (APA)
Mahfood Haddad, Toufik& Anantha Narayanan, Mahesh& Shaw, Krista E.& Vivekanandan, Renuga. 2015. Fatal Case of Probable Invasive Aspergillosis after Five Years of Heart Transplant: A Case Report and Review of the Literature. Case Reports in Infectious Diseases،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1058766
Modern Language Association (MLA)
Mahfood Haddad, Toufik…[et al.]. Fatal Case of Probable Invasive Aspergillosis after Five Years of Heart Transplant: A Case Report and Review of the Literature. Case Reports in Infectious Diseases No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1058766
American Medical Association (AMA)
Mahfood Haddad, Toufik& Anantha Narayanan, Mahesh& Shaw, Krista E.& Vivekanandan, Renuga. Fatal Case of Probable Invasive Aspergillosis after Five Years of Heart Transplant: A Case Report and Review of the Literature. Case Reports in Infectious Diseases. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1058766
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1058766