Isolated Central Nervous System Relapse in Chronic Myeloid Leukemia

Abstract EN

Chronic myeloid leukemia is a myeloproliferative disorder that has three distinguished phases:chronic, accelerated, and blastic.

In extremely rare cases, the blast phase can affect the centralnervous system without concomitant bone marrow involvement.

We report the case of a patientwith chronic myeloid leukemia who, despite having achieved complete cytogenetic remission in thebone marrow for several years, experienced a blast crisis of the central nervous system following anepisode of infectious meningoencephalitis.