Probable Hydrochlorothiazide-Induced Myopericarditis: First Case Reported
Joint Authors
Mooss, Aryan
Mahfood Haddad, Toufik
Abuzaid, Ahmed
Nawaz, Muhammad Sarfraz
Upadhyay, Smrithy
Bellamkonda, Pallavi
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-15
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Hydrochlorothiazide has never been reported as a reason for myopericarditis.
An African American female, with past history of hypertension, coronary artery disease, and sulfa allergy, presented with indolent onset and retrosternal chest pain which was positional, pleuritic, and unresponsive to sublingual nitroglycerin.
Her medications included hydrochlorothiazide (HCTZ) which was started three months ago for uncontrolled hypertension.
Significant laboratory parameters included erythrocyte sedimentation rate (ESR) of 47 mm/hr and peak troponin of 0.26 ng/mL.
Transthoracic echocardiogram (TTE) revealed preserved ejection fraction with no segmental wall motion abnormalities; however, it showed moderate pericardial effusion without tamponade physiology.
We hypothesize that this myopericarditis could be due to HCTZ allergic reaction after all other common etiologies have been ruled out.
There is a scarcity of the literature regarding HCTZ as an etiology for pericardial disease, with only one case reported as presumed hydrochlorothiazide-induced pericardial effusion.
Management involves discontinuation of HCTZ and starting anti-inflammatory therapy.
American Psychological Association (APA)
Mahfood Haddad, Toufik& Nawaz, Muhammad Sarfraz& Abuzaid, Ahmed& Upadhyay, Smrithy& Bellamkonda, Pallavi& Mooss, Aryan. 2015. Probable Hydrochlorothiazide-Induced Myopericarditis: First Case Reported. Case Reports in Medicine،Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1058812
Modern Language Association (MLA)
Mahfood Haddad, Toufik…[et al.]. Probable Hydrochlorothiazide-Induced Myopericarditis: First Case Reported. Case Reports in Medicine No. 2015 (2015), pp.1-3.
https://search.emarefa.net/detail/BIM-1058812
American Medical Association (AMA)
Mahfood Haddad, Toufik& Nawaz, Muhammad Sarfraz& Abuzaid, Ahmed& Upadhyay, Smrithy& Bellamkonda, Pallavi& Mooss, Aryan. Probable Hydrochlorothiazide-Induced Myopericarditis: First Case Reported. Case Reports in Medicine. 2015. Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1058812
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1058812