Copious Podocyturia without Proteinuria and with Normal Renal Function in a Young Adult with Fabry Disease
Joint Authors
Trimarchi, Hernán
Pomeranz, Vanesa
Forrester, Mariano
Canzonieri, R.
Muryan, A.
Schiel, A.
Araoz, A.
Andrews, J.
Rengel, T.
Zotta, E.
Karl, A.
Lombi, Fernando
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-21
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
The time for starting a patient with Fabry disease on enzyme replacement therapy is still a matter of debate, particularly when no overt classical clinical signs or symptoms are present.
With respect to Fabry nephropathy, a dual problem coexists: the reluctance of many nephrologists to start enzyme replacement infusion until signs of renal disease appear as the appearance of proteinuria or an elevation in serum creatinine and the lack of validated biomarkers of early renal damage.
In this regard, proteinuria is nowadays considered as an early and appropriate marker of kidney disease and of cardiovascular morbidity and mortality.
However, in this report we demonstrate that podocyturia antedates the classical appearance of proteinuria and could be considered as an even earlier biomarker of kidney damage.
Podocyturia may be a novel indication for the initiation of therapy in Fabry disease.
American Psychological Association (APA)
Trimarchi, Hernán& Canzonieri, R.& Muryan, A.& Schiel, A.& Araoz, A.& Forrester, Mariano…[et al.]. 2015. Copious Podocyturia without Proteinuria and with Normal Renal Function in a Young Adult with Fabry Disease. Case Reports in Nephrology،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1058953
Modern Language Association (MLA)
Trimarchi, Hernán…[et al.]. Copious Podocyturia without Proteinuria and with Normal Renal Function in a Young Adult with Fabry Disease. Case Reports in Nephrology No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1058953
American Medical Association (AMA)
Trimarchi, Hernán& Canzonieri, R.& Muryan, A.& Schiel, A.& Araoz, A.& Forrester, Mariano…[et al.]. Copious Podocyturia without Proteinuria and with Normal Renal Function in a Young Adult with Fabry Disease. Case Reports in Nephrology. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1058953
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1058953