Pulmonary Limited MPO-ANCA Microscopic Polyangiitis and Idiopathic Lung Fibrosis in a Patient with a Diagnosis of IgA Nephropathy
Joint Authors
Tilanus, Alwin
Van der Niepen, Patricia
Geers, Caroline
Wissing, Karl Martin
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-07-22
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
We present a case of a male patient with chronic renal insufficiency, due to crescentic glomerulonephritis with IgA deposits, who successively developed (idiopathic) thrombocytopenic purpura (ITP) and MPO-ANCA microscopic polyangiitis (MPA) with pulmonary fibrosis.
The patient presented with cough, weight loss, and dyspnea on exertion.
CT imaging and pulmonary function tests were compatible with interstitial pneumonitis with pulmonary fibrosis.
Laboratory results showed high MPO-ANCA titers; the urinary sediment was bland.
The patient was treated successfully with cyclophosphamide and methyl-prednisolone.
This unique case illustrates the diagnostic and therapeutic challenges of an unusual presentation of microscopic polyangiitis presenting first as isolated kidney disease with recurrence in the form of pneumonitis without renal involvement, in association with renal IgA deposits and ITP as coexisting autoimmune conditions.
American Psychological Association (APA)
Tilanus, Alwin& Van der Niepen, Patricia& Geers, Caroline& Wissing, Karl Martin. 2015. Pulmonary Limited MPO-ANCA Microscopic Polyangiitis and Idiopathic Lung Fibrosis in a Patient with a Diagnosis of IgA Nephropathy. Case Reports in Nephrology،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1058963
Modern Language Association (MLA)
Tilanus, Alwin…[et al.]. Pulmonary Limited MPO-ANCA Microscopic Polyangiitis and Idiopathic Lung Fibrosis in a Patient with a Diagnosis of IgA Nephropathy. Case Reports in Nephrology No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1058963
American Medical Association (AMA)
Tilanus, Alwin& Van der Niepen, Patricia& Geers, Caroline& Wissing, Karl Martin. Pulmonary Limited MPO-ANCA Microscopic Polyangiitis and Idiopathic Lung Fibrosis in a Patient with a Diagnosis of IgA Nephropathy. Case Reports in Nephrology. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1058963
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1058963