![](/images/graphics-bg.png)
Acute Dysphasia and Reversible Cognitive Decline in a Patient with Probable Cerebral Amyloid Angiopathy-Related Inflammation
Joint Authors
Rigney, Louise
Sebire, Dale
Cordato, Dennis
Source
Case Reports in Neurological Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-02
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Cerebral amyloid angiopathy related inflammation (CAAri) is becoming increasingly recognised as a subset of cerebral amyloid angiopathy (CAA).
CAAri generally presents with subacute cognitive decline, headaches, seizures, behavioral changes, and focal neurological deficits.
We describe a patient who developed acute dysphasia and reversible cognitive decline due to probable CAAri.
CT brain showed bilateral vasogenic edema in the cerebral hemispheres, predominantly involving the parietal and temporal lobes, left greater than right without enhancement.
Magnetic resonance brain imaging showed extensive multifocal areas of subcortical white matter T2 hyperintensity in the frontal and temporal regions with associated mass effect, negligible enhancement, and multiple foci of microhemorrhage on susceptibility weighted imaging sequences consistent with a diagnosis of probable CAAri.
She responded dramatically to a course of intravenous methylprednisolone followed by further immunosuppression with pulse intravenous cyclophosphamide.
Her dysphasia resolved within 5 days of intravenous methylprednisolone therapy.
Her MMSE improved from 11/30 at day 5 of admission to 28/30 at 6-month follow-up.
The notable features of our case were the unusual CT findings, which were inconsistent with stroke and diagnostic utility of susceptibility-weighted magnetic resonance imaging in confirming the diagnosis which allowed for prompt institution of immunosuppression.
American Psychological Association (APA)
Rigney, Louise& Sebire, Dale& Cordato, Dennis. 2015. Acute Dysphasia and Reversible Cognitive Decline in a Patient with Probable Cerebral Amyloid Angiopathy-Related Inflammation. Case Reports in Neurological Medicine،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1058995
Modern Language Association (MLA)
Rigney, Louise…[et al.]. Acute Dysphasia and Reversible Cognitive Decline in a Patient with Probable Cerebral Amyloid Angiopathy-Related Inflammation. Case Reports in Neurological Medicine No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1058995
American Medical Association (AMA)
Rigney, Louise& Sebire, Dale& Cordato, Dennis. Acute Dysphasia and Reversible Cognitive Decline in a Patient with Probable Cerebral Amyloid Angiopathy-Related Inflammation. Case Reports in Neurological Medicine. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1058995
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1058995