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Propranolol for Paroxysmal Sympathetic Hyperactivity with Lateralizing Hyperhidrosis after Stroke
Joint Authors
Siefferman, Jason W.
Lai, George
Source
Case Reports in Neurological Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-18
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Brain injury can lead to impaired cortical inhibition of the hypothalamus, resulting in increased sympathetic nervous system activation.
Symptoms of paroxysmal sympathetic hyperactivity may include hyperthermia, tachycardia, tachypnea, vasodilation, and hyperhidrosis.
We report the case of a 41-year-old man who suffered from a left middle cerebral artery stroke and subsequently developed central fever, contralateral temperature change, and hyperhidrosis.
His symptoms abated with low-dose propranolol and then returned upon discontinuation.
Restarting propranolol again stopped his symptoms.
This represents the first report of propranolol being used for unilateral dysautonomia after stroke.
Propranolol is a lipophilic nonselective beta-blocker which easily crosses the blood-brain barrier and may be used to treat paroxysmal sympathetic hyperactivity.
American Psychological Association (APA)
Siefferman, Jason W.& Lai, George. 2015. Propranolol for Paroxysmal Sympathetic Hyperactivity with Lateralizing Hyperhidrosis after Stroke. Case Reports in Neurological Medicine،Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1059027
Modern Language Association (MLA)
Siefferman, Jason W.& Lai, George. Propranolol for Paroxysmal Sympathetic Hyperactivity with Lateralizing Hyperhidrosis after Stroke. Case Reports in Neurological Medicine No. 2015 (2015), pp.1-3.
https://search.emarefa.net/detail/BIM-1059027
American Medical Association (AMA)
Siefferman, Jason W.& Lai, George. Propranolol for Paroxysmal Sympathetic Hyperactivity with Lateralizing Hyperhidrosis after Stroke. Case Reports in Neurological Medicine. 2015. Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1059027
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1059027