Central Pontine Myelinolysis with Minimal Hyponatremia in the Setting of AIDS
Joint Authors
Carrington, Joseph M.
Sanchez, Galo
Berkeley, Jennifer L.
Source
Case Reports in Neurological Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-2, 2 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-29
Country of Publication
Egypt
No. of Pages
2
Main Subjects
Abstract EN
Central pontine myelinolysis (CPM) is classically attributed to overly rapid correction of profound hyponatremia.
However, there are case reports of this disease in the setting of normal serum sodium or minimal hyponatremia.
These cases have been hypothesized to be secondary to other metabolic disturbances such as hyperglycemia or hypophosphatemia.
Eunatremic CPM has also been described in patients with advanced acquired immune deficiency syndrome (AIDS).
The mortality risk in this special population is significantly higher than those with hyponatremia-associated CPM, but the mechanisms are unclear.
We discuss a case of a man with AIDS who developed CPM with minimal hyponatremia and no other metabolic disturbances.
Common variables within this population, such as hypoalbuminemia and lymphoma, are discussed as potential factors contributing to the pathophysiology.
Reporting these atypical cases is crucial to our understanding of how to prevent future cases.
American Psychological Association (APA)
Carrington, Joseph M.& Sanchez, Galo& Berkeley, Jennifer L.. 2015. Central Pontine Myelinolysis with Minimal Hyponatremia in the Setting of AIDS. Case Reports in Neurological Medicine،Vol. 2015, no. 2015, pp.1-2.
https://search.emarefa.net/detail/BIM-1059028
Modern Language Association (MLA)
Carrington, Joseph M.…[et al.]. Central Pontine Myelinolysis with Minimal Hyponatremia in the Setting of AIDS. Case Reports in Neurological Medicine No. 2015 (2015), pp.1-2.
https://search.emarefa.net/detail/BIM-1059028
American Medical Association (AMA)
Carrington, Joseph M.& Sanchez, Galo& Berkeley, Jennifer L.. Central Pontine Myelinolysis with Minimal Hyponatremia in the Setting of AIDS. Case Reports in Neurological Medicine. 2015. Vol. 2015, no. 2015, pp.1-2.
https://search.emarefa.net/detail/BIM-1059028
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1059028