ESBL Escherichia coli Ventriculitis after Aneurysm Clipping: A Rare and Difficult Therapeutic Challenge
Joint Authors
Source
Case Reports in Neurological Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-29
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Background.
Extended spectrum beta-lactamase (ESBL) produced Escherichia coli (E.
coli) ventriculitis is a rare infection of the central nervous system, with increasing rarity in the adult population.
The therapeutic strategy to achieve cure may need to involve a combination of intraventricular and intravenous (IV) therapy.
Objective.
To describe a case of ESBL E.
coli meningitis/ventriculitis in an adult and outline the antimicrobial therapy that leads to cure.
Methods.
We retrospectively reviewed the records of a patient admitted to the neurosurgical department for aneurysmal subarachnoid hemorrhage, who developed ESBL E.
coli ventriculitis.
Results.
A 55-year-old female, admitted for a Fisher grade 3, World Federation of Neurological Surgeons grade 1, subarachnoid hemorrhage, developed ESBL E.
coli ventriculitis requiring a combination of intraventricular gentamicin and high dose intravenous meropenem for clearance.
Cerebrospinal fluid clearance occurred at 7 days after initiation of combined therapy.
The patient remained shunt dependent.
Conclusions.
Meningitis and ventriculitis caused by ESBL E.
coli species are rare and pose significant challenges to the treating physician.
Early consideration for combined intraventricular and IV therapy should be made.
American Psychological Association (APA)
Zeiler, F. A.& Silvaggio, J.. 2015. ESBL Escherichia coli Ventriculitis after Aneurysm Clipping: A Rare and Difficult Therapeutic Challenge. Case Reports in Neurological Medicine،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1059054
Modern Language Association (MLA)
Zeiler, F. A.& Silvaggio, J.. ESBL Escherichia coli Ventriculitis after Aneurysm Clipping: A Rare and Difficult Therapeutic Challenge. Case Reports in Neurological Medicine No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1059054
American Medical Association (AMA)
Zeiler, F. A.& Silvaggio, J.. ESBL Escherichia coli Ventriculitis after Aneurysm Clipping: A Rare and Difficult Therapeutic Challenge. Case Reports in Neurological Medicine. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1059054
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1059054