Drug-Induced Thrombocytopenia following a Transvaginal Oocyte Retrieval for In Vitro Fertilization

Abstract EN

Drug-induced immune thrombocytopenia has been associated with hundreds of medications and can lead to devastating consequences for the patient.

We present a case of a healthy 33-year-old female undergoing in vitro fertilization who developed a severe drug-induced thrombocytopenia, petechiae, and a large hemoperitoneum after receiving Cefazolin antibiotic prophylaxis for a transvaginal oocyte retrieval.

The patient was admitted to the intensive care unit for resuscitation with blood products.

The presence of drug-dependent platelet antibodies to Cefazolin was confirmed serologically.