Primary Vaginal Myeloid Sarcoma: A Rare Case Report and Review of the Literature
Joint Authors
Modi, Gaurang
Panchal, Harsha
Anand, Asha
Parikh, Sonia
Revannasiddaiah, Swaroop
Jain, Pritam
Sarkar, Malay
Madabhavi, Irappa
Patel, Apurva
Source
Case Reports in Obstetrics and Gynecology
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-01-18
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Myeloid sarcoma (chloroma, granulocytic sarcoma, or extramedullary myeloid tumour) is an extramedullary mass forming neoplasm composed of myeloid precursor cells.
It is usually associated with myeloproliferative disorders but very rarely may precede the onset of leukemia.
Here, we are presenting a rare case of primary vaginal myeloid sarcoma in a geriatric female patient without initial presentation of acute myeloid leukemia (AML).
A 68-year-old female patient with ECOG Performance Score of 1 presented with pervaginal bleeding for 20 days.
On colposcopic examination, she was found to have mass in the anterior fornix of vagina.
A punch biopsy specimen revealed chloromatous infiltration of the vagina.
LCA (leukocyte common antigen), MPO (myeloperoxidase), and c-kit were strongly positive on IHC (immunohistochemistry).
The patient’s routine blood investigations were normal including peripheral smear, lactose dehydrogenase, uric acid, 2D echocardiography, conventional cytogenetics, bone marrow aspiration, and biopsy.
The patient was given 4 cycles of decitabine (Decitex, manufactured by Sun Pharmaceutical Industries Limited, India), 20 mg/m2 for 5 days at an interval of 28 days.
There was a partial response to decitabine according to RECIST criteria.
As decitabine therapy was well tolerated, we are continuing in the same way until disease progression without any complications.
The patient is undergoing regular follow-up at our centre.
American Psychological Association (APA)
Modi, Gaurang& Madabhavi, Irappa& Panchal, Harsha& Patel, Apurva& Anand, Asha& Parikh, Sonia…[et al.]. 2015. Primary Vaginal Myeloid Sarcoma: A Rare Case Report and Review of the Literature. Case Reports in Obstetrics and Gynecology،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1059225
Modern Language Association (MLA)
Modi, Gaurang…[et al.]. Primary Vaginal Myeloid Sarcoma: A Rare Case Report and Review of the Literature. Case Reports in Obstetrics and Gynecology No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1059225
American Medical Association (AMA)
Modi, Gaurang& Madabhavi, Irappa& Panchal, Harsha& Patel, Apurva& Anand, Asha& Parikh, Sonia…[et al.]. Primary Vaginal Myeloid Sarcoma: A Rare Case Report and Review of the Literature. Case Reports in Obstetrics and Gynecology. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1059225
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1059225