A Peculiar Case of the Abscopal Effect: Radioactive Iodine Therapy Incidentally Palliating Marginal Zone Lymphoma
Joint Authors
Kornas, Robert
Shields, Sarah-Kim
Goldman, Lyle
Source
Case Reports in Oncological Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-02
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
The abscopal effect is an extremely rare phenomenon occurring when irradiation or treatment of a primary tumor burden not only results in debulking of the targeted site but also reduces tumor size at distant sites from the intended treatment area.
We present the abscopal effect occurring in a patient with low-grade marginal zone lymphoma who subsequently received radioactive iodine therapy for papillary thyroid carcinoma.
She was 67 years old when a routine complete blood count at her primary care physician’s office yielded a persistent leukocytosis of 14,500/μL with lymphocytosis of 9,870/μL.
Immunophenotyping and fluorescence in situ hybridization (FISH) analysis confirmed low-grade marginal zone lymphoma.
Over eight years, her peak leukocyte and lymphocyte counts were 24,100/μL and 18,100/μL, respectively.
Subsequently, she was diagnosed with papillary thyroid carcinoma after presenting with a new complaint of dysphagia.
A total thyroidectomy was performed, followed by 172.1 millicuries of oral I-131 sodium iodine radioactive ablation therapy.
Following treatment, her leukocyte and lymphocyte counts were 3,100/μL and 1,100/μL, respectively.
Over the next four years, her leukocyte and lymphocyte counts remained within normal limits and she remained symptom free.
To our knowledge, there has never been a published report describing the use of radioactive iodine causing abscopal effect benefits for patients with underlying lymphoproliferative diseases.
American Psychological Association (APA)
Kornas, Robert& Shields, Sarah-Kim& Goldman, Lyle. 2015. A Peculiar Case of the Abscopal Effect: Radioactive Iodine Therapy Incidentally Palliating Marginal Zone Lymphoma. Case Reports in Oncological Medicine،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1059256
Modern Language Association (MLA)
Kornas, Robert…[et al.]. A Peculiar Case of the Abscopal Effect: Radioactive Iodine Therapy Incidentally Palliating Marginal Zone Lymphoma. Case Reports in Oncological Medicine No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1059256
American Medical Association (AMA)
Kornas, Robert& Shields, Sarah-Kim& Goldman, Lyle. A Peculiar Case of the Abscopal Effect: Radioactive Iodine Therapy Incidentally Palliating Marginal Zone Lymphoma. Case Reports in Oncological Medicine. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1059256
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1059256