Metastatic Colonic Adenocarcinoma in Breast: Report of Two Cases and Review of the Literature
Joint Authors
Kothadia, Jiten P.
Arju, Rezina
Kaminski, Monica
Ankireddypalli, Arvind
Duddempudi, Sushil
Chow, Jonathan
Giashuddin, Shah
Source
Case Reports in Oncological Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-25
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Metastatic adenocarcinoma to the breast from an extramammary site is extremely rare.
In the literature, the most current estimate is that extramammary metastases account for only 0.43% of all breast malignancies and that, of these extramammary sites, colon cancer metastases form a very small subset.
Most commonly seen metastasis in breast is from a contralateral breast carcinoma, followed by metastasis from hematopoietic neoplasms, malignant melanoma, sarcoma, lung, prostate, and ovary and gastric neoplasms.
Here we present two rare cases, in which colonic adenocarcinomas were found to metastasize to the breast.
In both cases, core biopsies were obtained from the suspicious areas identified on mammogram.
Histopathology revealed neoplastic proliferation of atypical glandular components within benign breast parenchyma which were morphologically consistent with metastatic adenocarcinoma.
By immunohistochemical staining, it was confirmed that the neoplastic components were immunoreactive to colonic markers and nonreactive to breast markers, thus further supporting the morphologic findings.
It is extremely important to make this distinction between primary breast cancer and a metastatic process, in order to provide the most effective and appropriate treatment for the patient and to avoid any harmful or unnecessary surgical procedures.
American Psychological Association (APA)
Kothadia, Jiten P.& Arju, Rezina& Kaminski, Monica& Ankireddypalli, Arvind& Duddempudi, Sushil& Chow, Jonathan…[et al.]. 2015. Metastatic Colonic Adenocarcinoma in Breast: Report of Two Cases and Review of the Literature. Case Reports in Oncological Medicine،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1059281
Modern Language Association (MLA)
Kothadia, Jiten P.…[et al.]. Metastatic Colonic Adenocarcinoma in Breast: Report of Two Cases and Review of the Literature. Case Reports in Oncological Medicine No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1059281
American Medical Association (AMA)
Kothadia, Jiten P.& Arju, Rezina& Kaminski, Monica& Ankireddypalli, Arvind& Duddempudi, Sushil& Chow, Jonathan…[et al.]. Metastatic Colonic Adenocarcinoma in Breast: Report of Two Cases and Review of the Literature. Case Reports in Oncological Medicine. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1059281
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1059281