Is It Safe to Restart Antivascular Endothelial Growth Factor Therapy in Patients with Renal Cell Carcinoma after Cardiac Ischemia?
Joint Authors
Zhao, Bo
Wood, Laura S.
James, Karen
Rini, Brian I.
Source
Case Reports in Oncological Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-13
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Agents targeting vascular endothelial growth factor (VEGF) represent active drugs in treating patients with advanced renal cell carcinoma (RCC).
Studies have shown that sunitinib and axitinib can be associated with cardiac toxicity.
Whether these agents should be restarted in patients who experience cardiac ischemia remains uncertain.
Here, we present three patients with metastatic RCC who restarted sunitinib or axitinib after intervention of active ischemic cardiac disease without causing subsequent relevant cardiac events.
This experience suggests that these agents can be continued after management of cardiac ischemia.
American Psychological Association (APA)
Zhao, Bo& Wood, Laura S.& James, Karen& Rini, Brian I.. 2015. Is It Safe to Restart Antivascular Endothelial Growth Factor Therapy in Patients with Renal Cell Carcinoma after Cardiac Ischemia?. Case Reports in Oncological Medicine،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1059313
Modern Language Association (MLA)
Zhao, Bo…[et al.]. Is It Safe to Restart Antivascular Endothelial Growth Factor Therapy in Patients with Renal Cell Carcinoma after Cardiac Ischemia?. Case Reports in Oncological Medicine No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1059313
American Medical Association (AMA)
Zhao, Bo& Wood, Laura S.& James, Karen& Rini, Brian I.. Is It Safe to Restart Antivascular Endothelial Growth Factor Therapy in Patients with Renal Cell Carcinoma after Cardiac Ischemia?. Case Reports in Oncological Medicine. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1059313
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1059313