Diagnostic Challenges in Primary Hepatocellular Carcinoma: Case Reports and Review of the Literature
Joint Authors
Zuwała-Jagiełło, Jolanta
Pazgan-Simon, Monika
Simon, Krzysztof
Serafinska, Sylwia
Janocha-Litwin, Justyna
Source
Case Reports in Oncological Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-01
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Hepatocellular carcinoma is the fifth most common malignancy and the third leading mortality cause worldwide.
It typically develops secondarily to liver cirrhosis, due to hepatitis B or C infection, alcohol abuse, metabolic disease, and so forth.
According to the American Association for the Study of Liver Diseases (AASLD) guidelines, which constitute diagnostic standards, the diagnosis of primary hepatocellular carcinoma (HCC) should be based on contrast-enhanced imaging.
Lesion hyperenhancement should be observed throughout the arterial phase, followed by the washout during the venous phase.
The diagnosis can also be based on the histopathological evaluation of liver biopsy specimen.
Although the standards are clear, we often see patients with advanced HCC in clinical practice, who cannot be offered any effective treatment.
Patients with chronic liver disease, presenting with inconclusive and changeable test results, constitute a separate problem.
In such cases the diagnostic process is typically long-term and delayed.
In this paper we present three case reports where the diagnosis could not be made promptly and the patients died as a result of a delayed diagnostic process.
American Psychological Association (APA)
Pazgan-Simon, Monika& Serafinska, Sylwia& Janocha-Litwin, Justyna& Simon, Krzysztof& Zuwała-Jagiełło, Jolanta. 2015. Diagnostic Challenges in Primary Hepatocellular Carcinoma: Case Reports and Review of the Literature. Case Reports in Oncological Medicine،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1059323
Modern Language Association (MLA)
Pazgan-Simon, Monika…[et al.]. Diagnostic Challenges in Primary Hepatocellular Carcinoma: Case Reports and Review of the Literature. Case Reports in Oncological Medicine No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1059323
American Medical Association (AMA)
Pazgan-Simon, Monika& Serafinska, Sylwia& Janocha-Litwin, Justyna& Simon, Krzysztof& Zuwała-Jagiełło, Jolanta. Diagnostic Challenges in Primary Hepatocellular Carcinoma: Case Reports and Review of the Literature. Case Reports in Oncological Medicine. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1059323
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1059323