Nontargeted Effect after Radiotherapy in a Patient with Non-Small Cell Lung Cancer and Bullous Pemphigoid
Joint Authors
Nieder, Carsten
Al-Shibli, Khalid
Tollåli, Terje
Source
Case Reports in Oncological Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-09
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Purpose.
To describe tumor shrinkage of nonirradiated lung metastases in a patient with non-small cell lung cancer.
Case Report.
The patient had a concurrent autoimmune condition, bullous pemphigoid, which was clinically exacerbated during radiotherapy of mediastinal and axillary lymph node metastases.
He also developed a series of infections during and after irradiation, and we hypothesize that the immunological events during this phase might have influenced the size of the nonirradiated metastases.
Conclusion.
Ionizing radiation generates inflammatory signals and, in principle, could provide both tumor-specific antigens from dying cells and maturation stimuli that are necessary for dendritic cells’ activation of tumor-specific T cells.
Even if the detailed mechanisms causing nontargeted immune modulatory effects in individual patients are poorly understood, clinical development of radioimmunotherapy is underway.
American Psychological Association (APA)
Nieder, Carsten& Al-Shibli, Khalid& Tollåli, Terje. 2015. Nontargeted Effect after Radiotherapy in a Patient with Non-Small Cell Lung Cancer and Bullous Pemphigoid. Case Reports in Oncological Medicine،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1059337
Modern Language Association (MLA)
Nieder, Carsten…[et al.]. Nontargeted Effect after Radiotherapy in a Patient with Non-Small Cell Lung Cancer and Bullous Pemphigoid. Case Reports in Oncological Medicine No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1059337
American Medical Association (AMA)
Nieder, Carsten& Al-Shibli, Khalid& Tollåli, Terje. Nontargeted Effect after Radiotherapy in a Patient with Non-Small Cell Lung Cancer and Bullous Pemphigoid. Case Reports in Oncological Medicine. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1059337
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1059337