Sub-Tenon Injections of Triamcinolone Acetonide Had Limited Effect on Cystoid Macular Edema Secondary to Nanoparticle Albumin-Bound-Paclitaxel (Abraxane)
Joint Authors
Fukuchi, Takeo
Matsuoka, Naoki
Hasebe, Hiruma
Mayama, Tetsuji
Source
Case Reports in Ophthalmological Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-23
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Purpose.
To report the first case of cystoid macular edema (CME) induced by nanoparticle albumin-bound- (nab-) paclitaxel treated with sub-Tenon injections of triamcinolone acetonide (STTA) with detailed long-term follow-up.
Case.
A 39-year-old Japanese woman with breast cancer presents with decreased vision in both eyes while receiving nab-paclitaxel.
Two STTA treatments were administered for persistent CME in her right eye.
Central retinal thickness (CRT) of the treated eye decreased after the first STTA, but there was no change after the second STTA.
CRT of the other eye and bilateral visual acuity (VA) showed no change after each treatment.
However, this patient experienced gradual recovery of visual function after nab-paclitaxel treatment was completed, 3 months after the second STTA.
Improvements in VA and CRT did not overlap in time.
Moreover, there was a big improvement time lag in VA between the eyes.
Conclusion.
Cessation of nab-paclitaxel could lead to resolution of CME more than STTA, although STTA had some effect.
Since nab-paclitaxel has been recently approved for treating more types of malignancies, the number of the patients with this CME is expected to increase in the near future.
Patients and physicians should understand this side effect and prepare for other treatment options.
American Psychological Association (APA)
Matsuoka, Naoki& Hasebe, Hiruma& Mayama, Tetsuji& Fukuchi, Takeo. 2015. Sub-Tenon Injections of Triamcinolone Acetonide Had Limited Effect on Cystoid Macular Edema Secondary to Nanoparticle Albumin-Bound-Paclitaxel (Abraxane). Case Reports in Ophthalmological Medicine،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1059351
Modern Language Association (MLA)
Matsuoka, Naoki…[et al.]. Sub-Tenon Injections of Triamcinolone Acetonide Had Limited Effect on Cystoid Macular Edema Secondary to Nanoparticle Albumin-Bound-Paclitaxel (Abraxane). Case Reports in Ophthalmological Medicine No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1059351
American Medical Association (AMA)
Matsuoka, Naoki& Hasebe, Hiruma& Mayama, Tetsuji& Fukuchi, Takeo. Sub-Tenon Injections of Triamcinolone Acetonide Had Limited Effect on Cystoid Macular Edema Secondary to Nanoparticle Albumin-Bound-Paclitaxel (Abraxane). Case Reports in Ophthalmological Medicine. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1059351
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1059351