Clinical Findings and Genetic Expression Profiling of Three Pigmented Lesions of the Optic Nerve
Joint Authors
Wildner, Andrea
Murray, Timothy G.
Latiff, Azeema
Ehlies, Fiona
Gold, Aaron S.
de Alba, Manuel A.
Villegas, Victor M.
Source
Case Reports in Ophthalmological Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-23
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Optic disk melanocytoma is a primary tumor of the optic disk that represents a clinical diagnostic challenge due to its similarities with melanoma.
Purpose.
The authors present three cases in which genetic expression profiling was used to identify tumor prognosis of optic disk melanocytoma.
Case Series.
In two cases fine-needle aspiration biopsy was performed to obtain tissue through a transvitreal route into the apex of the tumor while the patient underwent pars plana vitrectomy, laser ablation, phacoemulsification with posterior chamber intraocular lens implantation, and intravitreal triamcinolone acetonide.
In the other case the tissue was obtained after definite enucleation.
Conclusion.
Genetic expression profiling is a useful diagnostic tool for classification and can provide vital information to the ocular oncologist regarding prognosis.
American Psychological Association (APA)
de Alba, Manuel A.& Villegas, Victor M.& Gold, Aaron S.& Wildner, Andrea& Ehlies, Fiona& Latiff, Azeema…[et al.]. 2015. Clinical Findings and Genetic Expression Profiling of Three Pigmented Lesions of the Optic Nerve. Case Reports in Ophthalmological Medicine،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1059386
Modern Language Association (MLA)
de Alba, Manuel A.…[et al.]. Clinical Findings and Genetic Expression Profiling of Three Pigmented Lesions of the Optic Nerve. Case Reports in Ophthalmological Medicine No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1059386
American Medical Association (AMA)
de Alba, Manuel A.& Villegas, Victor M.& Gold, Aaron S.& Wildner, Andrea& Ehlies, Fiona& Latiff, Azeema…[et al.]. Clinical Findings and Genetic Expression Profiling of Three Pigmented Lesions of the Optic Nerve. Case Reports in Ophthalmological Medicine. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1059386
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1059386