Single Intravitreal Aflibercept Injection for Unilateral Acute Nonarteritic Ischemic Optic Neuropathy

Abstract EN

Acute nonarteritic ischemic optic neuropathy (ANAION) is the most common optic neuropathy in the elderly population without a well-established treatment.

A 67-year-old man with a sudden painless visual loss in his left eye of one-day duration was diagnosed to have left ANAION.

Next day, 2 mg aflibercept injection was injected intravitreally in OS.

Visual acuity improved to 7/10 from 1/10 a week after the injection.

Mean retinal nerve fiber layer thickness (RNFLT) was reduced to 159,7 μm from 182,4 μm at the first week.

Visual fields improved dramatically during the follow-up of three months.

The aim of this study is to present a case having ANAION treated with a single intravitreal aflibercept injection and discuss the place of intravitreal anti-VEGF injections in the treatment of armamentarium of ANAION.