Corneal Collagen Cross-Linking in Pellucid Marginal Degeneration: 2 Patients, 4 Eyes

Abstract EN

Purpose.

To report the long-term results of corneal collagen cross-linking (CXL) with riboflavin and ultraviolet-A irradiation in 4 eyes of 2 patients affected by pellucid marginal degeneration (PMD).

Methods.

This study involved the retrospective analysis of 4 eyes of 2 patients with PMD that underwent CXL treatment.

Of the eyes, three had only CXL treatment and one had CXL treatment after an intrastromal corneal ring segment implantation.

We have pre- and postoperatively evaluated uncorrected distance visual acuity (UDVA), best corrected distance visual acuity (BCDVA), corneal topography (Pentacam), specular microscopy, and pachymetry.

Results.

Patient 1 was a woman, aged 35, and Patient 2 was a man, aged 33.

The right eye of Patient 1 showed an improvement in her BCDVA, from 16/40 to 18/20 in 15 months, and her left eye improved from 12/20 to 18/20 in 20 months.

Patient 2’s right eye showed an improvement in his BCDVA, from 18/20 to 20/20 in 43 months, and his left eye improved from 16/20 to 18/20 in 22 months.

No complications were recorded during or after the treatment.

Conclusion.

CXL is a safe tool for the management of PMD, and it can help to stop the progression of this disease.