HPV Type 6 and 18 Coinfection in a Case of Adult-Onset Laryngeal Papillomatosis: Immunization with Gardasil
Joint Authors
Piana, Andrea
Sotgiu, Giovanni
Fancello, Virginia
Melis, Andrea
Castiglia, Paolo
Cossu, Andrea
Bozzo, Corrado
King, Emma Victoria
Meloni, Francesco
Source
Case Reports in Otolaryngology
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-11-29
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Laryngeal papillomatosis (LP) is a rare human papillomavirus (HPV) related disease that often requires multiple surgical interventions and residual impairment of voice is almost inevitable.
We report the case of a patient with adult onset recurrent LP, showing moderate dysplasia and coinfection with HPV types 6 and 18.
The tetravalent HPV vaccine Gardasil was prescribed off label, with the aim of triggering an immunogenic response and consequently reducing the probability of further recurrences.
The patient was followed for 9 months with no sign of relapse of his LP.
The postexposure use of the anti-HPV vaccine could represent a promising therapeutic agent in established LP.
Unfortunately, the potential efficacy of this new therapeutic option in this situation has been suggested only by isolated case reports.
Further controlled studies, with a longer follow-up and a larger sample size, are needed to assess efficacy of Gardasil in LP.
American Psychological Association (APA)
Fancello, Virginia& Melis, Andrea& Piana, Andrea& Castiglia, Paolo& Cossu, Andrea& Sotgiu, Giovanni…[et al.]. 2015. HPV Type 6 and 18 Coinfection in a Case of Adult-Onset Laryngeal Papillomatosis: Immunization with Gardasil. Case Reports in Otolaryngology،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1059677
Modern Language Association (MLA)
Fancello, Virginia…[et al.]. HPV Type 6 and 18 Coinfection in a Case of Adult-Onset Laryngeal Papillomatosis: Immunization with Gardasil. Case Reports in Otolaryngology No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1059677
American Medical Association (AMA)
Fancello, Virginia& Melis, Andrea& Piana, Andrea& Castiglia, Paolo& Cossu, Andrea& Sotgiu, Giovanni…[et al.]. HPV Type 6 and 18 Coinfection in a Case of Adult-Onset Laryngeal Papillomatosis: Immunization with Gardasil. Case Reports in Otolaryngology. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1059677
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1059677