Invasive Aspergillosis Associated with a Foreign Body

Abstract EN

Invasive aspergillosis is a serious complication in immunocompromised individuals.

It is associated with a high mortality rate, which demands a combined approach involving radical surgery and antifungal therapy.

Here, we describe a patient who presented with nonspecific fever, refractory to antimicrobial agents.

Though it primarily involved the nasal cavity and sinuses, it perforated into the oral cavity causing palatal changes.

Surprisingly, a foreign body was found in the involved tissues that might have acted as a nidus of infection.

A sufficient dose (3 mg/kg/day) of liposomal amphotericin B was initiated soon after a thorough debridement procedure and the patient survived.