Costello Syndrome with Severe Nodulocystic Acne: Unexpected Significant Improvement of Acanthosis Nigricans after Oral Isotretinoin Treatment
Joint Authors
Sriboonnark, Leelawadee
Arora, Harleen
Falto-Aizpurua, Leyre
Choudhary, Sonal
Connelly, Elizabeth Alvarez
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-28
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
We report the case of 17-year-old female diagnosed with Costello syndrome.
Genetic testing provided a proof with G12S mutation in the HRAS gene since 3 years of age with a presentation of severe nodulocystic acne on her face.
After 2 months of oral isotretinoin treatment, improvement in her acne was observed.
Interestingly, an unexpected significant improvement of acanthosis nigricans on her neck and dorsum of her hands was found as well.
We present this case as a successful treatment option by using oral isotretinoin for the treatment of acanthosis nigricans in Costello syndrome patients.
American Psychological Association (APA)
Sriboonnark, Leelawadee& Arora, Harleen& Falto-Aizpurua, Leyre& Choudhary, Sonal& Connelly, Elizabeth Alvarez. 2015. Costello Syndrome with Severe Nodulocystic Acne: Unexpected Significant Improvement of Acanthosis Nigricans after Oral Isotretinoin Treatment. Case Reports in Pediatrics،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1059817
Modern Language Association (MLA)
Sriboonnark, Leelawadee…[et al.]. Costello Syndrome with Severe Nodulocystic Acne: Unexpected Significant Improvement of Acanthosis Nigricans after Oral Isotretinoin Treatment. Case Reports in Pediatrics No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1059817
American Medical Association (AMA)
Sriboonnark, Leelawadee& Arora, Harleen& Falto-Aizpurua, Leyre& Choudhary, Sonal& Connelly, Elizabeth Alvarez. Costello Syndrome with Severe Nodulocystic Acne: Unexpected Significant Improvement of Acanthosis Nigricans after Oral Isotretinoin Treatment. Case Reports in Pediatrics. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1059817
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1059817