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Interstitial Lung Disease in Werner Syndrome: A Case Report of a 55-Year-Old Male Patient
Joint Authors
Goletto, Tiphaine
Crockett, Flora
Aractingi, Selim
Toper, Cecile
Senet, Patricia
Cadranel, Jacques
Naccache, Jean-Marc
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-12-16
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Werner syndrome (WS) is a progeroid or premature aging syndrome characterized by early onset of age-related pathologies and cancer.
The average life expectancy of affected people is 52.8 years and tends to increase.
The major causes of death are malignancy and myocardial infarction.
Increased telomere attrition and decay are thought to play a causative role in the clinical and pathological manifestations of the disease.
Although telomere length, with or without germline mutation, is known to be associated with interstitial lung disease, the latter is not associated with WS.
To the best of our knowledge, we report the first case describing a WS patient with fatal ILD.
This case suggests that older patients with WS could develop ILD.
Clinical outcome of WS patients may thus be improved by counselling them regarding smoking cessation or other exposure and by proposing antifibrotic therapy.
American Psychological Association (APA)
Goletto, Tiphaine& Crockett, Flora& Aractingi, Selim& Toper, Cecile& Senet, Patricia& Cadranel, Jacques…[et al.]. 2015. Interstitial Lung Disease in Werner Syndrome: A Case Report of a 55-Year-Old Male Patient. Case Reports in Pulmonology،Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1059871
Modern Language Association (MLA)
Goletto, Tiphaine…[et al.]. Interstitial Lung Disease in Werner Syndrome: A Case Report of a 55-Year-Old Male Patient. Case Reports in Pulmonology No. 2015 (2015), pp.1-3.
https://search.emarefa.net/detail/BIM-1059871
American Medical Association (AMA)
Goletto, Tiphaine& Crockett, Flora& Aractingi, Selim& Toper, Cecile& Senet, Patricia& Cadranel, Jacques…[et al.]. Interstitial Lung Disease in Werner Syndrome: A Case Report of a 55-Year-Old Male Patient. Case Reports in Pulmonology. 2015. Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1059871
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1059871