Organizing Pneumonia Associated with Pegylated Interferon α and Ribavirin Therapy

Abstract EN

Hepatitis C virus infection is the leading cause of chronic liver disease in the United States of America.

Pegylated interferon α and ribavirin combination is the mainstay of treatment.

Severe pulmonary toxicities are rarely reported.

We report here a case of severe form of organizing pneumonia secondary to pegylated interferon α therapy presenting as acute respiratory failure.

Patient has near complete recovery with withdrawal of pegylated interferon α and steroid therapy.

We report this case to raise the awareness of this rare but potentially life-threatening pulmonary complication of pegylated interferon α therapy.