Unusual Presentation of Recurrent Early Stage Endometrial Carcinoma 28 Years after Primary Surgery
Joint Authors
Chiusa, Luigi
Franchello, Alessandro
Fronda, Gianruggero
Deiro, Giacomo
Fiore, Alessia
Cassine, Davide
Molinaro, Luca
Galati, Sara
Resegotti, Andrea
Silvestri, Stefano
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-12-09
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Endometrial carcinoma is the most common neoplasia of female genital tract.
The prognosis of early stage disease (FIGO I and FIGO II) is excellent: recurrence after surgery is less than 15%, most of which are reported within 3 years after primary treatment.
Herein we report a case of late rectal recurrence from FIGO Ib endometrial adenocarcinoma.
Patient had also familiar and personal history of colonic adenocarcinoma and previous findings of microsatellite instability (MSI); molecular analysis evidenced heterozygotic somatic mutation in MLH1 gene.
Twenty-eight years after hysterectomy and bilateral salpingoovariectomy, a rectal wall mass was detected during routine colonoscopy.
Patients underwent CT scan, pelvic MRI, and rectal EUS with FNA: histopathological and immunohistochemical analysis revealed differentiated carcinoma cells of endometrial origin.
No neoadjuvant treatment was planned and low rectal anterior resection with protective colostomy was performed; histology confirmed rectal lesion as metastasis from endometrial carcinoma.
Recurrence of early stage endometrial carcinoma after a long period from primary surgery is possible.
It is important to keep in mind this possibility in order to set a correct diagnostic and therapeutic algorithm, including preoperative immunohistochemical staining, and to plan a prolonged follow-up program.
American Psychological Association (APA)
Franchello, Alessandro& Fronda, Gianruggero& Deiro, Giacomo& Fiore, Alessia& Cassine, Davide& Molinaro, Luca…[et al.]. 2015. Unusual Presentation of Recurrent Early Stage Endometrial Carcinoma 28 Years after Primary Surgery. Case Reports in Surgery،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1060020
Modern Language Association (MLA)
Franchello, Alessandro…[et al.]. Unusual Presentation of Recurrent Early Stage Endometrial Carcinoma 28 Years after Primary Surgery. Case Reports in Surgery No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1060020
American Medical Association (AMA)
Franchello, Alessandro& Fronda, Gianruggero& Deiro, Giacomo& Fiore, Alessia& Cassine, Davide& Molinaro, Luca…[et al.]. Unusual Presentation of Recurrent Early Stage Endometrial Carcinoma 28 Years after Primary Surgery. Case Reports in Surgery. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1060020
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1060020