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A Rare Case of Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia
Joint Authors
Ofikwu, Godwin
Mani, Vishnu R.
Rajabalan, Ajai
Adu, Albert
Ahmed, Leaque
Vega, Dennis
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-11-02
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) is a rare clinical condition with only about 100 cases reported in the literature.
It is characterized by primary hyperplasia of pulmonary neuroendocrine cells (PNECs) which are specialized epithelial cells located throughout the entire respiratory tract, from the trachea to the terminal airways.
DIPNECH appears in various forms that include diffuse proliferation of scattered neuroendocrine cells, small nodules, or a linear proliferation.
It is usually seen in middle-aged, nonsmoking women with symptoms of cough, dyspnea, and wheezing.
We present a 45-year-old, nonsmoking woman who presented with symptoms of DIPNECH associated with bilateral pulmonary nodules and left hilar adenopathy.
Of interest, DIPNECH in our patient was associated with metastatic pulmonary carcinoids, papillary carcinoma of the left breast, oncocytoma and angiomyolipoma of her left kidney, and cortical nodules suggestive of tuberous sclerosis.
She had video assisted thoracoscopic surgery (VATS), modified radical mastectomy with reconstruction, and radical nephrectomy.
She is currently symptom-free most of the time with over two years of follow-up.
American Psychological Association (APA)
Ofikwu, Godwin& Mani, Vishnu R.& Rajabalan, Ajai& Adu, Albert& Ahmed, Leaque& Vega, Dennis. 2015. A Rare Case of Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia. Case Reports in Surgery،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1060034
Modern Language Association (MLA)
Ofikwu, Godwin…[et al.]. A Rare Case of Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia. Case Reports in Surgery No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1060034
American Medical Association (AMA)
Ofikwu, Godwin& Mani, Vishnu R.& Rajabalan, Ajai& Adu, Albert& Ahmed, Leaque& Vega, Dennis. A Rare Case of Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia. Case Reports in Surgery. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1060034
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1060034