Achalasia in Pregnancy: Botulinum Toxin A Injection of Lower Esophageal Sphincter
Joint Authors
Hooft, Nicole
Schmidt, Emily S.
Bremner, Ross M.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-07-02
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Background.
Achalasia, a rare esophageal motility disorder that may cause malnutrition during pregnancy, can result in fetal and maternal morbidity and mortality.
Many medical treatment regimens are contraindicated or not tolerated during pregnancy, and surgery is generally avoided due to potential risks to the fetus.
Case Report.
Severe, medically refractory achalasia in a 23-year-old pregnant woman that caused malnutrition was successfully managed by administering a botulinum toxin A injection to the lower esophageal sphincter.
The injection was performed at approximately 14 weeks’ gestation and the patient reported clinically significant relief from dysphagia.
She gained weight and ultimately delivered a healthy baby girl at term, but her symptoms returned a few months postpartum.
She underwent a second treatment of botulinum toxin A injection, but it offered only one month of relief.
Roughly eight months after delivery, the patient underwent a laparoscopic extended Heller myotomy and Dor fundoplication.
The patient resumed a normal diet one week postoperatively, and her baby has had no complications.
Conclusion.
This is only the second reported case of botulinum toxin A injection being used to treat achalasia in pregnancy.
This treatment proved to be a safe temporary alternative without the risks of surgery and anesthesia during pregnancy.
American Psychological Association (APA)
Hooft, Nicole& Schmidt, Emily S.& Bremner, Ross M.. 2015. Achalasia in Pregnancy: Botulinum Toxin A Injection of Lower Esophageal Sphincter. Case Reports in Surgery،Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1060038
Modern Language Association (MLA)
Hooft, Nicole…[et al.]. Achalasia in Pregnancy: Botulinum Toxin A Injection of Lower Esophageal Sphincter. Case Reports in Surgery No. 2015 (2015), pp.1-3.
https://search.emarefa.net/detail/BIM-1060038
American Medical Association (AMA)
Hooft, Nicole& Schmidt, Emily S.& Bremner, Ross M.. Achalasia in Pregnancy: Botulinum Toxin A Injection of Lower Esophageal Sphincter. Case Reports in Surgery. 2015. Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1060038
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1060038