17-Week Delay Surgery after Chemoradiation in Rectal Cancer with Complete Pathological Response
Joint Authors
Gomes, Manuel T.
Moreno, Filipa
Rocha, Anabela
Santos, Marisa D.
Lopes, Carlos
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-22
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Neoadjuvant chemoradiation (CRT) followed by curative surgery still remains the standard of care for locally advanced rectal cancer (LARC).
The main purpose of this multimodal treatment is to achieve a complete pathological tumor response (ypCR), with better survival.
The surgery delay after CRT completion seems to increase tumor response and ypCR rate.
Usually, time intervals range from 8 to 12 weeks, but the maximum tumor regression may not be seen in rectal adenocarcinomas until several months after CRT.
About this issue, we report a case of a 52-year-old man with LARC treated with neoadjuvant CRT who developed, one month after RT completion, an acute myocardial infarction.
The need to increase the interval between CRT and surgery for 17 weeks allowed a curative surgery without morbidity and an unexpected complete tumor response in the resected specimen (given the parameters presented in pelvic magnetic resonance imaging (MRI) performed 11 weeks after radiotherapy completion).
American Psychological Association (APA)
Santos, Marisa D.& Gomes, Manuel T.& Moreno, Filipa& Rocha, Anabela& Lopes, Carlos. 2015. 17-Week Delay Surgery after Chemoradiation in Rectal Cancer with Complete Pathological Response. Case Reports in Surgery،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1060145
Modern Language Association (MLA)
Santos, Marisa D.…[et al.]. 17-Week Delay Surgery after Chemoradiation in Rectal Cancer with Complete Pathological Response. Case Reports in Surgery No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1060145
American Medical Association (AMA)
Santos, Marisa D.& Gomes, Manuel T.& Moreno, Filipa& Rocha, Anabela& Lopes, Carlos. 17-Week Delay Surgery after Chemoradiation in Rectal Cancer with Complete Pathological Response. Case Reports in Surgery. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1060145
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1060145