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Hepatocellular Carcinoma with Osteoclast-Like Giant Cells: Report of the Seventh Case in the Literature
Joint Authors
Dioscoridi, Lorenzo
Bisogni, Damiano
Freschi, Giancarlo
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-22
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Hepatocellular carcinoma with osteoclast-like giant cells is extremely rare, and only six cases have been previously reported.
Its histogenesis is at the moment controversial.
The authors report a case of hepatocellular carcinoma with osteoclast-like giant cells found in a 74-year-old woman.
The patient came with a dull pain in the right upper abdominal quadrants due to a liver neoplasm described at CT scan.
A wedge resection of the fifth hepatic segment with appendectomy, omentectomy, and debulking of the major peritoneal implants was performed.
Histologically, the diagnosis of hepatocellular carcinoma with high grade differentiation associated with giant osteoclast-like cells was done without any evidence of hepatitis or cirrhosis in the surrounding hepatic parenchyma.
Immunohistochemistry was positive for CD10 and CD68 and in situ hybridization revealed the expression of receptor activator of nuclear factor-kappa B (RANK) in the giant cells and receptor activator of nuclear factor-kappa B ligand (RANKL) in the tumor cells.
American Psychological Association (APA)
Dioscoridi, Lorenzo& Bisogni, Damiano& Freschi, Giancarlo. 2015. Hepatocellular Carcinoma with Osteoclast-Like Giant Cells: Report of the Seventh Case in the Literature. Case Reports in Surgery،Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1060150
Modern Language Association (MLA)
Dioscoridi, Lorenzo…[et al.]. Hepatocellular Carcinoma with Osteoclast-Like Giant Cells: Report of the Seventh Case in the Literature. Case Reports in Surgery No. 2015 (2015), pp.1-3.
https://search.emarefa.net/detail/BIM-1060150
American Medical Association (AMA)
Dioscoridi, Lorenzo& Bisogni, Damiano& Freschi, Giancarlo. Hepatocellular Carcinoma with Osteoclast-Like Giant Cells: Report of the Seventh Case in the Literature. Case Reports in Surgery. 2015. Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1060150
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1060150