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Premalignant and Malignant Skin Lesions in Two Recipients of Vascularized Composite Tissue Allografts (Face, Hands)
Joint Authors
Petruzzo, Palmina
Kanitakis, Jean
Gazarian, Aram
Testelin, Sylvie
Devauchelle, Bernard
Badet, Lionel
Dubernard, Jean-Michel
Morelon, Emmanuel
Source
Case Reports in Transplantation
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-13
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Recipients of solid organ transplants (RSOT) have a highly increased risk for developing cutaneous premalignant and malignant lesions, favored by the lifelong immunosuppression.
Vascularized composite tissue allografts (VCA) have been introduced recently, and relevant data are sparse.
Two patients with skin cancers (one with basal cell carcinoma and one with squamous cell carcinomas) have been so far reported in this patient group.
Since 2000 we have been following 9 recipients of VCA (3 face, 6 bilateral hands) for the development of rejection and complications of the immunosuppressive treatment.
Among the 9 patients, one face-grafted recipient was diagnosed with nodular-pigmented basal cell carcinoma of her own facial skin 6 years after graft, and one patient with double hand allografts developed disseminated superficial actinic porokeratosis, a potentially premalignant dermatosis, on her skin of the arm and legs.
Similar to RSOT, recipients of VCA are prone to develop cutaneous premalignant and malignant lesions.
Prevention should be applied through sun-protective measures, regular skin examination, and early treatment of premalignant lesions.
American Psychological Association (APA)
Kanitakis, Jean& Petruzzo, Palmina& Gazarian, Aram& Testelin, Sylvie& Devauchelle, Bernard& Badet, Lionel…[et al.]. 2015. Premalignant and Malignant Skin Lesions in Two Recipients of Vascularized Composite Tissue Allografts (Face, Hands). Case Reports in Transplantation،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1060184
Modern Language Association (MLA)
Kanitakis, Jean…[et al.]. Premalignant and Malignant Skin Lesions in Two Recipients of Vascularized Composite Tissue Allografts (Face, Hands). Case Reports in Transplantation No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1060184
American Medical Association (AMA)
Kanitakis, Jean& Petruzzo, Palmina& Gazarian, Aram& Testelin, Sylvie& Devauchelle, Bernard& Badet, Lionel…[et al.]. Premalignant and Malignant Skin Lesions in Two Recipients of Vascularized Composite Tissue Allografts (Face, Hands). Case Reports in Transplantation. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1060184
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1060184