Perivascular Wall Tumor in the Brain of a Dog

Abstract EN

A 9-year-old spayed female German shepherd mixed-breed dog presented for seizures.

Magnetic resonance imaging revealed an irregularly marginated intraparenchymal cerebral mass.

Microscopic examination of brain tissue collected postmortem demonstrated perivascular whorling and interwoven bundles of spindle-shaped cells.

On immunohistochemistry, the tumor cells tested positive for vimentin and negative for factor VIII-related antigen, CD18, CD45, CD3, CD20, GFAP, S-100, and desmin.

Immunohistochemistry results, in combination with histopathologic morphology, were suggestive of a perivascular wall tumor.

To the authors’ knowledge, this is the first case report to utilize both histopathology and immunohistochemistry to describe a perivascular wall tumor in the brain of a dog.