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Antithrombotic Therapy in Patients with Acute Coronary Syndrome in the Intermountain Heart Collaborative Study
Joint Authors
Knight, Stacey
Klaskala, Winslow
Woller, Scott C.
Horne, Benjamin D.
Bunch, T. Jared
Le, Viet T.
Mills, Roger M.
Muhlestein, Joseph B.
Source
Cardiology Research and Practice
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-01-08
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Objective.
To determine factors associated with single antiplatelet (SAP) or dual antiplatelet (DAP) therapy and anticoagulants (AC) use in hospital and after discharge among patients with acute coronary syndrome (ACS).
Methods.
We evaluated 5,294 ACS patients in the Intermountain Heart Collaborative Study from 2004 to 2009.
Multivariable logistic regressions were used to determine predictors of AC or AP use.
Results.
In hospital, 99% received an AC, 79% DAP, and 19% SAP; 78% had DAP + AC.
Coronary stents were the strongest predictors of DAP use in hospital compared to SAP ( P < 0.001 ).
After discharge, 77% received DAP, 20% SAP, and 9% AC; 5% had DAP + AC.
DAP compared to SAP was less likely for patients on AC (odds ratio [OR] = 0.30, P < 0.0001 ) after discharge.
Placement of a stent increased the likelihood of DAP (bare metal: OR = 54.8, P < 0.0001 ; drug eluting: OR = 59.4, P < 0.0001 ).
923 had atrial fibrillation and 337 had a history of venous thromboembolism; these patients had increased use of AC (29% and 40%, resp.).
Conclusion.
While in-hospital use of AC was nearly universal, postdischarge AC use was rare.
Concern for providing the best antithrombotic therapy, while maintaining an acceptable bleeding risk, may explain the selection decisions.
American Psychological Association (APA)
Knight, Stacey& Klaskala, Winslow& Woller, Scott C.& Horne, Benjamin D.& Bunch, T. Jared& Le, Viet T.…[et al.]. 2015. Antithrombotic Therapy in Patients with Acute Coronary Syndrome in the Intermountain Heart Collaborative Study. Cardiology Research and Practice،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1060355
Modern Language Association (MLA)
Knight, Stacey…[et al.]. Antithrombotic Therapy in Patients with Acute Coronary Syndrome in the Intermountain Heart Collaborative Study. Cardiology Research and Practice No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1060355
American Medical Association (AMA)
Knight, Stacey& Klaskala, Winslow& Woller, Scott C.& Horne, Benjamin D.& Bunch, T. Jared& Le, Viet T.…[et al.]. Antithrombotic Therapy in Patients with Acute Coronary Syndrome in the Intermountain Heart Collaborative Study. Cardiology Research and Practice. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1060355
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1060355