Determinants and Regression Equations for the Calculation of z Scores of Left Ventricular Tissue Doppler Longitudinal Indexes in a Healthy Italian Pediatric Population
Joint Authors
Fibbi, Veronica
Zuppiroli, Alfredo
Favilli, Silvia
Spaziani, Gaia
Calabri, Giovanni B.
Pollini, Iva
Chiappa, Enrico
Ballo, Piercarlo
Source
Cardiology Research and Practice
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-11-22
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Aim.
We investigated the predictors of tissue Doppler left ventricular (LV) longitudinal indexes in a healthy Italian pediatric population and established normative data and regression equations for the calculation of z scores.
Methods and Results.
A total of 369 healthy subjects aged 1–17 years (age of 6.4 ± 1.1 years, 49.1% female) underwent echocardiography.
LV peak longitudinal velocity at systole (s'), early diastole (e'), and late diastole (a') was determined by tissue Doppler.
The ratio of peak early diastolic LV filling velocity to e' was calculated.
Age was the only independent determinant of s' (β=0.491, p<0.0001) and the strongest determinant of e' (β=0.334, p<0.0001) and E/e' (β=-0.369, p<0.0001).
Heart rate was the main determinant of a' (β=0.265, p<0.0001).
Male gender showed no effects except for a weak association with lateral s', suggesting no need of gender-specific reference ranges.
Age-specific reference ranges, regression equations, and scatterplots for the calculation of z scores were determined for each index.
Conclusion.
In a pediatric Italian population, age was the strongest determinant of LV longitudinal dynamics.
The availability of age-specific normality data for the calculation of z scores may allow for correctly detecting LV dysfunction in pediatric pathological populations.
American Psychological Association (APA)
Fibbi, Veronica& Ballo, Piercarlo& Favilli, Silvia& Spaziani, Gaia& Calabri, Giovanni B.& Pollini, Iva…[et al.]. 2015. Determinants and Regression Equations for the Calculation of z Scores of Left Ventricular Tissue Doppler Longitudinal Indexes in a Healthy Italian Pediatric Population. Cardiology Research and Practice،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1060361
Modern Language Association (MLA)
Fibbi, Veronica…[et al.]. Determinants and Regression Equations for the Calculation of z Scores of Left Ventricular Tissue Doppler Longitudinal Indexes in a Healthy Italian Pediatric Population. Cardiology Research and Practice No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1060361
American Medical Association (AMA)
Fibbi, Veronica& Ballo, Piercarlo& Favilli, Silvia& Spaziani, Gaia& Calabri, Giovanni B.& Pollini, Iva…[et al.]. Determinants and Regression Equations for the Calculation of z Scores of Left Ventricular Tissue Doppler Longitudinal Indexes in a Healthy Italian Pediatric Population. Cardiology Research and Practice. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1060361
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1060361