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Integrated Use of Statistical-Based Approaches and Computational Intelligence Techniques for Tumors Classification Using Microarray
Joint Authors
Hou, Chia-Ding
Shao, Yuehjen E.
Source
Discrete Dynamics in Nature and Society
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-01
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
With the recent development of biotechnologies, cDNA microarray chips are increasingly applied in cancer research.
Microarray experiments can lead to a more thorough grasp of the molecular variations among tumors because they can allow the monitoring of expression levels in cells for thousands of genes simultaneously.
Accordingly, how to successfully discriminate the classes of tumors using gene expression data is an urgent research issue and plays an important role in carcinogenesis.
To refine the large dimension of the genes data and effectively classify tumor classes, this study proposes several hybrid discrimination procedures that combine the statistical-based techniques and computational intelligence approaches to discriminate the tumor classes.
A real microarray data set was used to demonstrate the performance of the proposed approaches.
In addition, the results of cross-validation experiments reveal that the proposed two-stage hybrid models are more efficient in discriminating the acute leukemia classes than the established single stage models.
American Psychological Association (APA)
Hou, Chia-Ding& Shao, Yuehjen E.. 2015. Integrated Use of Statistical-Based Approaches and Computational Intelligence Techniques for Tumors Classification Using Microarray. Discrete Dynamics in Nature and Society،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1060436
Modern Language Association (MLA)
Hou, Chia-Ding& Shao, Yuehjen E.. Integrated Use of Statistical-Based Approaches and Computational Intelligence Techniques for Tumors Classification Using Microarray. Discrete Dynamics in Nature and Society No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1060436
American Medical Association (AMA)
Hou, Chia-Ding& Shao, Yuehjen E.. Integrated Use of Statistical-Based Approaches and Computational Intelligence Techniques for Tumors Classification Using Microarray. Discrete Dynamics in Nature and Society. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1060436
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1060436