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Hemoglobin A1c Level Is Not Related to the Severity of Atherosclerosis in Patients with Acute Coronary Syndrome
Joint Authors
Hao, Guanghua
Wang, Xinhong
Han, Zhenhua
Li, Yongqin
Dong, Xin
Wang, Congxia
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-07-16
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
The relationship between hemoglobin A1c (HbA1c) levels and the extent of coronary artery stenosis in patients with acute coronary syndrome (ACS) remains uncertain.
The present study aimed to assess the correlation of HbA1c level with angiographic coronary atherosclerosis.
Methods.
292 consecutive ACS patients were enrolled and stratified into three groups according to HbA1c levels (group 1: <6.0%, n = 137 ; group 2: 6.0–6.4%, n = 67 ; group 3: ≥6.5%, n = 88 ).
The severity of coronary arteriosclerosis was assessed by Gensini score.
The relationship between HbA1c and Gensini score was analyzed by multiple variables analysis.
Results.
HbA1c level was not associated with the severity of CAD assessed by Gensini score in patients with ACS, even after the adjustment for other risk factors.
However, NT-proBNP, ApoA1 and LVEF levels were independent predictors for CAD severity.
Moreover, HbA1c level was not associated with the risk of high Gensini score (>40) by logistic regression analysis.
Diabetes mellitus (DM) and LVEF levels were two independent risk factors for high Gensini score.
Conclusions.
HbA1c level is not a significant and independent marker for the severity of angiography in ACS patients, even in high-risk patients.
American Psychological Association (APA)
Wang, Xinhong& Han, Zhenhua& Hao, Guanghua& Li, Yongqin& Dong, Xin& Wang, Congxia. 2015. Hemoglobin A1c Level Is Not Related to the Severity of Atherosclerosis in Patients with Acute Coronary Syndrome. Disease Markers،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1060874
Modern Language Association (MLA)
Wang, Xinhong…[et al.]. Hemoglobin A1c Level Is Not Related to the Severity of Atherosclerosis in Patients with Acute Coronary Syndrome. Disease Markers No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1060874
American Medical Association (AMA)
Wang, Xinhong& Han, Zhenhua& Hao, Guanghua& Li, Yongqin& Dong, Xin& Wang, Congxia. Hemoglobin A1c Level Is Not Related to the Severity of Atherosclerosis in Patients with Acute Coronary Syndrome. Disease Markers. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1060874
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1060874