Twenty-Four-Hour Urine Osmolality as a Physiological Index of Adequate Water Intake
Joint Authors
Perrier, Erica T.
Buendia-Jimenez, Inmaculada
Vecchio, Mariacristina
Armstrong, Lawrence E.
Tack, Ivan
Klein, Alexis
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-18
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
While associations exist between water, hydration, and disease risk, research quantifying the dose-response effect of water on health is limited.
Thus, the water intake necessary to maintain optimal hydration from a physiological and health standpoint remains unclear.
The aim of this analysis was to derive a 24 h urine osmolality (UOsm) threshold that would provide an index of “optimal hydration,” sufficient to compensate water losses and also be biologically significant relative to the risk of disease.
Ninety-five adults (31.5 ± 4.3 years, 23.2 ± 2.7 kg·m−2) collected 24 h urine, provided morning blood samples, and completed food and fluid intake diaries over 3 consecutive weekdays.
A UOsm threshold was derived using 3 approaches, taking into account European dietary reference values for water; total fluid intake, and urine volumes associated with reduced risk for lithiasis and chronic kidney disease and plasma vasopressin concentration.
The aggregate of these approaches suggest that a 24 h urine osmolality ≤500 mOsm·kg−1 may be a simple indicator of optimal hydration, representing a total daily fluid intake adequate to compensate for daily losses, ensure urinary output sufficient to reduce the risk of urolithiasis and renal function decline, and avoid elevated plasma vasopressin concentrations mediating the increased antidiuretic effort.
American Psychological Association (APA)
Perrier, Erica T.& Buendia-Jimenez, Inmaculada& Vecchio, Mariacristina& Armstrong, Lawrence E.& Tack, Ivan& Klein, Alexis. 2015. Twenty-Four-Hour Urine Osmolality as a Physiological Index of Adequate Water Intake. Disease Markers،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1060880
Modern Language Association (MLA)
Perrier, Erica T.…[et al.]. Twenty-Four-Hour Urine Osmolality as a Physiological Index of Adequate Water Intake. Disease Markers No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1060880
American Medical Association (AMA)
Perrier, Erica T.& Buendia-Jimenez, Inmaculada& Vecchio, Mariacristina& Armstrong, Lawrence E.& Tack, Ivan& Klein, Alexis. Twenty-Four-Hour Urine Osmolality as a Physiological Index of Adequate Water Intake. Disease Markers. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1060880
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1060880