Vitamin D Is a Good Marker for Disease Activity of Rheumatoid Arthritis Disease
Joint Authors
Azzeh, Firas Sultan
Kensara, Osama Adnan
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-10
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Aim.
This study was conducted to find out the optimal vitamin D cutoff point in predicting activity of RA disease.
Materials and Methods.
One hundred and two rheumatoid arthritis Saudi patients of both genders were recruited in this study.
Vitamin D as 25-hydroxy-vitamin D [25(OH)D] was measured and serum level less than 20 ng/mL defined as deficient patient.
Disease activity was measured based on the disease activity score index of a 28-joint count (DAS28) using serum erythrocyte sedimentation rate levels.
Receiver operating characteristic (ROC) curves were used to determine the optimal vitamin D cutoff points for identifying disease activity.
Results.
It has been observed that vitamin D levels were lower (P < 0.05) in patients with high disease activity.
A significant inverse correlation between serum 25(OH)D levels and DAS28 (r = −0.277, P = 0.014) was shown.
ROC curves results showed that vitamin D less than 12.3 ng/mL predicted high disease activity, and vitamin D more than 17.9 ng/mL predicted low disease activity, with good sensitivity and accuracy results regarding vitamin D.
Conclusion.
Study results concluded that vitamin D is a good predictor of RA disease activity in Saudi patients.
American Psychological Association (APA)
Azzeh, Firas Sultan& Kensara, Osama Adnan. 2015. Vitamin D Is a Good Marker for Disease Activity of Rheumatoid Arthritis Disease. Disease Markers،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1060890
Modern Language Association (MLA)
Azzeh, Firas Sultan& Kensara, Osama Adnan. Vitamin D Is a Good Marker for Disease Activity of Rheumatoid Arthritis Disease. Disease Markers No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1060890
American Medical Association (AMA)
Azzeh, Firas Sultan& Kensara, Osama Adnan. Vitamin D Is a Good Marker for Disease Activity of Rheumatoid Arthritis Disease. Disease Markers. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1060890
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1060890