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Prognostic Utility of Vitamin D in Acute Coronary Syndrome Patients in Coastal Norway
Joint Authors
Harris, William S.
Naesgaard, Patrycja A.
Grundt, Heidi
Nilsen, Dennis W. T.
Pönitz, Volker
Brügger-Andersen, Trygve
Aarsetoey, Hildegunn
Staines, Harry
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-05
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Background.
An inverse relationship between cardiovascular risk and levels of vitamin D and omega-3 index may exist.
Objectives.
To evaluate the prognostic utility of serum 25-hydroxyvitamin D [25(OH)D] in 871 patients with suspected acute coronary syndrome (ACS) and to assess the seasonal correlation between 25(OH)D and the omega-3 index in 456 ACS patients from southwestern Norway.
Results.
In the univariate analysis the hazard ratio (HR) at 2-year follow-up for all-cause mortality in the highest as compared to the lowest quartile of 25(OH)D in the total population was 0.61 (95% confidence interval (CI), 0.37–1.00), P = 0.050 .
At 7-year follow-up, the corresponding HR for all-cause mortality was 0.66 (95% CI, 0.49–0.90), P = 0.008 , and for females alone 0.51 (95% CI, 0.32–0.83), P = 0.006 .
Quartile survival did not differ in the multivariable analysis, whereas 25(OH)D < 40 nM (<16 ng/mL) was found to be independently related to mortality.
Seasonal differences in 25(OH)D, but not for the omega-3 index, were noted, and the two biomarkers were positively correlated, especially during winter-spring; Pearson’s correlation coefficient was 0.358, P < 0.001 .
Conclusion.
Vitamin D levels are related to survival, especially in females, and correlate with the omega-3 index.
American Psychological Association (APA)
Naesgaard, Patrycja A.& Pönitz, Volker& Aarsetoey, Hildegunn& Brügger-Andersen, Trygve& Grundt, Heidi& Harris, William S.…[et al.]. 2015. Prognostic Utility of Vitamin D in Acute Coronary Syndrome Patients in Coastal Norway. Disease Markers،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1060894
Modern Language Association (MLA)
Naesgaard, Patrycja A.…[et al.]. Prognostic Utility of Vitamin D in Acute Coronary Syndrome Patients in Coastal Norway. Disease Markers No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1060894
American Medical Association (AMA)
Naesgaard, Patrycja A.& Pönitz, Volker& Aarsetoey, Hildegunn& Brügger-Andersen, Trygve& Grundt, Heidi& Harris, William S.…[et al.]. Prognostic Utility of Vitamin D in Acute Coronary Syndrome Patients in Coastal Norway. Disease Markers. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1060894
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1060894