Can Biomarkers Help to Diagnose Early Heart Failure with Preserved Ejection Fraction?
Joint Authors
Tomandl, Josef
Meluzín, Jaroslav
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-01-31
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Early heart failure with preserved ejection fraction (HFpEF) is a frequent disease, but its diagnosis is difficult and relies mostly on the evidence of left ventricular filling pressure (LVFP) elevation during exercise.
Several reports have suggested that natriuretic peptides plasma levels reflect exercise-induced increase in LVFP, but they still have significant limitations.
In this context, any new laboratory biomarker that can accurately reflect LVFP elevation during exercise is desirable.
Recently, cardiotrophin-1, soluble endoglin, ST2, growth differentiation factor 15, galectin-3, and other new laboratory markers associated with LVFP have emerged.
However, the current data on the relationship of these biomarkers and diastolic dysfunction are limited to resting conditions.
Therefore, their secretion deserves to be tested under the exercise to determine their potential role in making a diagnosis of early HFpEF.
American Psychological Association (APA)
Meluzín, Jaroslav& Tomandl, Josef. 2015. Can Biomarkers Help to Diagnose Early Heart Failure with Preserved Ejection Fraction?. Disease Markers،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1060941
Modern Language Association (MLA)
Meluzín, Jaroslav& Tomandl, Josef. Can Biomarkers Help to Diagnose Early Heart Failure with Preserved Ejection Fraction?. Disease Markers No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1060941
American Medical Association (AMA)
Meluzín, Jaroslav& Tomandl, Josef. Can Biomarkers Help to Diagnose Early Heart Failure with Preserved Ejection Fraction?. Disease Markers. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1060941
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1060941