Correlation between Sperm Parameters and Protein Expression of Antioxidative Defense Enzymes in Seminal Plasma: A Pilot Study
Joint Authors
Korac, Aleksandra
Stancic, Ana
Macanovic, Biljana
Garalejic, Eliana
Vucetic, Milica
Buzadzic, Biljana
Otasevic, Vesna
Jankovic, Aleksandra
Korac, Bato
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-01-27
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
Semen analysis is the cornerstone in the evaluation of male (in)fertility.
However, there are men with normal semen tests but with impaired fertilizing ability, as well as fertile men with poor sperm characteristics.
Thus, there is rising interest to find novel parameters that will help to predict and define the functional capacity of spermatozoa.
Methods.
We examined whether there is a correlation between semen parameters (count, progressive motility, and morphology) and protein expression/activity of antioxidative defense enzymes in seminal plasma from 10 normospermic subjects.
Results.
Sperm progressive motility was in positive correlation with seminal plasma protein expression of both superoxide dismutase (SOD) isoforms (MnSOD and CuZnSOD) and catalase.
Also, positive correlation was observed between sperm count and MnSOD protein expression, as well as between sperm morphology and protein expression of catalase in seminal plasma.
In contrast, protein expression of glutathione peroxidase was not in correlation with any sperm parameter, while its activity negatively correlated with sperm morphology and motility.
Conclusions.
These data suggest that evaluation of protein expression of antioxidative defense enzymes in seminal plasma might be of importance in the evaluation of male fertility status and that could be used as an additional biomarker along with classic semen analysis in assessment of semen quality.
American Psychological Association (APA)
Macanovic, Biljana& Vucetic, Milica& Jankovic, Aleksandra& Stancic, Ana& Buzadzic, Biljana& Garalejic, Eliana…[et al.]. 2015. Correlation between Sperm Parameters and Protein Expression of Antioxidative Defense Enzymes in Seminal Plasma: A Pilot Study. Disease Markers،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1060945
Modern Language Association (MLA)
Macanovic, Biljana…[et al.]. Correlation between Sperm Parameters and Protein Expression of Antioxidative Defense Enzymes in Seminal Plasma: A Pilot Study. Disease Markers No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1060945
American Medical Association (AMA)
Macanovic, Biljana& Vucetic, Milica& Jankovic, Aleksandra& Stancic, Ana& Buzadzic, Biljana& Garalejic, Eliana…[et al.]. Correlation between Sperm Parameters and Protein Expression of Antioxidative Defense Enzymes in Seminal Plasma: A Pilot Study. Disease Markers. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1060945
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1060945