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Association between Plasma Leptin and Estrogen in Female Patients of Amnestic Mild Cognitive Impairment
Joint Authors
Jia, Jianping
Xu, Jing Dong
Xing, Yi
Liu, Jianghong
Yin, Linlin
Wang, Lin
Li, Junjie
Yu, Zhipeng
Li, Fangyu
Gao, Ran
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-11-29
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Increasing evidences suggested the association between leptin and cognitive functions.
Estrogen is an important factor that regulates the production and metabolism of leptin.
However, little is known about the relationship between leptin and estrogen in mild cognitive impairment (MCI).
Plasma levels of leptin, total estradiol, and β-amyloid protein (Aβ) were measured in a total of 23 female amnestic MCI (aMCI) patients and 19 female cognitively normal controls.
This study showed that female aMCI patients had lower plasma levels of leptin and higher levels of estradiol compared to female normal controls.
Leptin and estradiol levels were not correlated with cognitive performances or plasma Aβ levels in either aMCI patients or normal controls.
There was a significant negative correlation between leptin and estrogen in female aMCI patients (r=-0.633, p=0.002) but not in female normal controls.
The potential mechanisms of this disease-stage-specific association between leptin and estrogen need further investigations.
American Psychological Association (APA)
Xing, Yi& Liu, Jianghong& Xu, Jing Dong& Yin, Linlin& Wang, Lin& Li, Junjie…[et al.]. 2015. Association between Plasma Leptin and Estrogen in Female Patients of Amnestic Mild Cognitive Impairment. Disease Markers،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1060946
Modern Language Association (MLA)
Xing, Yi…[et al.]. Association between Plasma Leptin and Estrogen in Female Patients of Amnestic Mild Cognitive Impairment. Disease Markers No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1060946
American Medical Association (AMA)
Xing, Yi& Liu, Jianghong& Xu, Jing Dong& Yin, Linlin& Wang, Lin& Li, Junjie…[et al.]. Association between Plasma Leptin and Estrogen in Female Patients of Amnestic Mild Cognitive Impairment. Disease Markers. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1060946
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1060946