Cardiovascular Biomarkers in Chronic Kidney Disease: State of Current Research and Clinical Applicability
Joint Authors
D’Marco, Luis
Bellasi, Antonio
Raggi, Paolo
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-05
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
The high incidence of cardiovascular events in chronic kidney disease (CKD) warrants an accurate evaluation of risk aimed at reducing the burden of disease and its consequences.
The use of biomarkers to identify patients at high risk has been in use in the general population for several decades and has received mixed reactions in the medical community.
Some practitioners have become staunch supporters and users while others doubt the utility of biomarkers and rarely measure them.
In CKD patients numerous markers similar to those used in the general population and others more specific to the uremic population have emerged; however their utility for routine clinical application remains to be fully elucidated.
The reproducibility and standardization of the serum assays are serious limitations to the broad implementation of these tests.
The lack of focused research and validation in randomized trials rather than ad hoc measurement of multiple serum markers in observational studies is also cause for concern related to the clinical applicability of these markers.
We review the current literature on biomarkers that may have a relevant role in field of nephrology.
American Psychological Association (APA)
D’Marco, Luis& Bellasi, Antonio& Raggi, Paolo. 2015. Cardiovascular Biomarkers in Chronic Kidney Disease: State of Current Research and Clinical Applicability. Disease Markers،Vol. 2015, no. 2015, pp.1-16.
https://search.emarefa.net/detail/BIM-1060986
Modern Language Association (MLA)
D’Marco, Luis…[et al.]. Cardiovascular Biomarkers in Chronic Kidney Disease: State of Current Research and Clinical Applicability. Disease Markers No. 2015 (2015), pp.1-16.
https://search.emarefa.net/detail/BIM-1060986
American Medical Association (AMA)
D’Marco, Luis& Bellasi, Antonio& Raggi, Paolo. Cardiovascular Biomarkers in Chronic Kidney Disease: State of Current Research and Clinical Applicability. Disease Markers. 2015. Vol. 2015, no. 2015, pp.1-16.
https://search.emarefa.net/detail/BIM-1060986
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1060986