Serum and Vitreous Concentrations of Omentin-1 in Diabetic Retinopathy

Joint Authors

Wan, Wencui
Li, Qiuming
Zhang, Fengyan
Zheng, Guangying
Lv, Yong
Wan, Guangming
Jin, Xuemin

Source

Disease Markers

Issue

Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-4, 4 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2015-09-03

Country of Publication

Egypt

No. of Pages

4

Main Subjects

Diseases

Abstract EN

Objective.

Omentin, a new discovered adipokine, is implicated to inhibit inflammation.

Inflammation is one important mechanism of diabetic retinopathy (DR).

The purpose of this work was to evaluate serum and vitreous concentrations of omentin-1 in patients with diabetic retinopathy (DR).

Methods.

This study enrolled 204 diabetic patients (60 without DR, 49 with NPDR, and 95 with PDR) and 65 control subjects.

Results.

Serum and vitreous omentin-1 levels in PDR patients were markedly decreased compared with those in the other three groups.

NPDR patients showed reduced vitreous omentin-1 compared with patients without DR.

In addition, control subjects had significantly higher levels of serum and vitreous omentin-1 compared with diabetic patients without DR, NPDR patients, and PDR patients.

In addition, serum/vitreous omentin-1 ratio was positively correlated with the development and severity of DR.

Conclusion.

Serum and vitreous omentin-1 levels, as well as serum/vitreous omentin-1 ratio, are correlated with the presence and severity of DR.

American Psychological Association (APA)

Wan, Wencui& Li, Qiuming& Zhang, Fengyan& Zheng, Guangying& Lv, Yong& Wan, Guangming…[et al.]. 2015. Serum and Vitreous Concentrations of Omentin-1 in Diabetic Retinopathy. Disease Markers،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1061030

Modern Language Association (MLA)

Wan, Wencui…[et al.]. Serum and Vitreous Concentrations of Omentin-1 in Diabetic Retinopathy. Disease Markers No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1061030

American Medical Association (AMA)

Wan, Wencui& Li, Qiuming& Zhang, Fengyan& Zheng, Guangying& Lv, Yong& Wan, Guangming…[et al.]. Serum and Vitreous Concentrations of Omentin-1 in Diabetic Retinopathy. Disease Markers. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1061030

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1061030