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Serum Chemerin Levels in relation to Osteoporosis and Bone Mineral Density: A Case-Control Study
Joint Authors
He, Jing
Li, Ji-Chun
Xie, Hua
Xu, Zhong-Hua
Sun, Ya-Wen
Shan, Qiao
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-15
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
To evaluate serum chemerin levels in patients with osteoporosis and healthy controls and to investigate the relationship between serum chemerin levels and bone mineral density (BMD).
Methods.
An age- and gender-matched case-control study was conducted.
Pearson’s correlation test was performed to investigate the relationship between serum chemerin levels and BMD.
Results.
There were 93 patients included in the osteoporosis group and 93 matched controls.
Serum chemerin level was significantly higher in patients with osteoporosis (87.27±5.80 ng/mL) than patients in control (71.13±5.12 ng/mL) (P<0.01).
There was a negative correlation between femoral bone mineral density and chemerin in both groups (R=-0.395, P<0.01 in osteoporosis group; R=-0.680, P<0.01 in control) and also a negative correlation between lumbar bone mineral density with chemerin in both groups (R=-0.306, P<0.01 in osteoporosis group; R=-0.362, P<0.01 in control).
Conclusions.
Patients with osteoporosis presented a higher level of serum chemerin, which witnessed an inverse correlation with BMD.
Further studies are needed to explore the role of chemerin in the pathophysiology of osteoporosis.
American Psychological Association (APA)
He, Jing& Li, Ji-Chun& Xie, Hua& Xu, Zhong-Hua& Sun, Ya-Wen& Shan, Qiao. 2015. Serum Chemerin Levels in relation to Osteoporosis and Bone Mineral Density: A Case-Control Study. Disease Markers،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1061040
Modern Language Association (MLA)
He, Jing…[et al.]. Serum Chemerin Levels in relation to Osteoporosis and Bone Mineral Density: A Case-Control Study. Disease Markers No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1061040
American Medical Association (AMA)
He, Jing& Li, Ji-Chun& Xie, Hua& Xu, Zhong-Hua& Sun, Ya-Wen& Shan, Qiao. Serum Chemerin Levels in relation to Osteoporosis and Bone Mineral Density: A Case-Control Study. Disease Markers. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1061040
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1061040