![](/images/graphics-bg.png)
Syndecan-1 in Cancer: Implications for Cell Signaling, Differentiation, and Prognostication
Joint Authors
Szatmári, Tünde
Ötvös, Rita
Hjerpe, Anders
Dobra, Katalin
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-09-01
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Syndecan-1, a cell surface heparan sulfate proteoglycan, is critically involved in the differentiation and prognosis of various tumors.
In this review, we highlight the synthesis, cellular interactions, and the signalling pathways regulated by syndecan-1.
The basal syndecan-1 level is also crucial for understanding the sequential changes involving malignant transformation, tumor progression, and advanced or disseminated cancer stages.
Moreover, we focus on the cellular localization of this proteoglycan as cell membrane anchored and/or shed, soluble syndecan-1 with stromal or nuclear accumulation and how this may carry different, highly tissue specific prognostic information for individual tumor types.
American Psychological Association (APA)
Szatmári, Tünde& Ötvös, Rita& Hjerpe, Anders& Dobra, Katalin. 2015. Syndecan-1 in Cancer: Implications for Cell Signaling, Differentiation, and Prognostication. Disease Markers،Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1061045
Modern Language Association (MLA)
Szatmári, Tünde…[et al.]. Syndecan-1 in Cancer: Implications for Cell Signaling, Differentiation, and Prognostication. Disease Markers No. 2015 (2015), pp.1-13.
https://search.emarefa.net/detail/BIM-1061045
American Medical Association (AMA)
Szatmári, Tünde& Ötvös, Rita& Hjerpe, Anders& Dobra, Katalin. Syndecan-1 in Cancer: Implications for Cell Signaling, Differentiation, and Prognostication. Disease Markers. 2015. Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1061045
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1061045