Impaired Fasting Glucose in Nondiabetic Range: Is It a Marker of Cardiovascular Risk Factor Clustering?
Joint Authors
Valentino, Giovanna
Kramer, Verónica
Orellana, Lorena
Bustamante, María José
Casasbellas, Cinthia
Adasme, Marcela
Salazar, Alejandra
Navarrete, Carlos
Acevedo, Mónica
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-04
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
Impaired fasting glucose (IFG) through the nondiabetic range (100–125 mg/dL) is not considered in the cardiovascular (CV) risk profile.
Aim.
To compare the clustering of CV risk factors (RFs) in nondiabetic subjects with normal fasting glucose (NFG) and IFG.
Material and Methods.
Cross-sectional study in 3739 nondiabetic subjects.
Demographics, medical history, and CV risk factors were collected and lipid profile, fasting glucose levels (FBG), C-reactive protein (hsCRP), blood pressure (BP), anthropometric measurements, and aerobic capacity were determined.
Results.
559 (15%) subjects had IFG: they had a higher mean age, BMI, waist circumference, non-HDL cholesterol, BP, and hsCRP (p<0.0001) and lower HDL (p<0.001) and aerobic capacity (p<0.001).
They also had a higher prevalence of hypertension (34% versus 25%; p<0.001), dyslipidemia (79% versus 74%; p<0.001), and obesity (29% versus 16%; p<0.001) and a higher Framingham risk score (8% versus 6%; p<0.001).
The probability of presenting 3 or more CV RFs adjusted by age and gender was significantly higher in the top quintile of fasting glucose (≥98 mg/dL; OR = 2.02; 1.62–2.51).
Conclusions.
IFG in the nondiabetic range is associated with increased cardiovascular RF clustering.
American Psychological Association (APA)
Valentino, Giovanna& Kramer, Verónica& Orellana, Lorena& Bustamante, María José& Casasbellas, Cinthia& Adasme, Marcela…[et al.]. 2015. Impaired Fasting Glucose in Nondiabetic Range: Is It a Marker of Cardiovascular Risk Factor Clustering?. Disease Markers،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1061046
Modern Language Association (MLA)
Valentino, Giovanna…[et al.]. Impaired Fasting Glucose in Nondiabetic Range: Is It a Marker of Cardiovascular Risk Factor Clustering?. Disease Markers No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1061046
American Medical Association (AMA)
Valentino, Giovanna& Kramer, Verónica& Orellana, Lorena& Bustamante, María José& Casasbellas, Cinthia& Adasme, Marcela…[et al.]. Impaired Fasting Glucose in Nondiabetic Range: Is It a Marker of Cardiovascular Risk Factor Clustering?. Disease Markers. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1061046
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1061046